magnesium-deficiency

A Critical Electrolyte - A Critical Difference

magnesium
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COMPARE MAG-TAB SR

Elemental magnesium (Mg++) and mEq per dose are not the same as absorbable Mg++.

The table below compares each product's solubility at the pH of the ileum and jejunum (where the majority of Mg++ is absorbed) and each product's bioavailability based on published studies. (12.30-34)
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ASYMPTOMATIC

"The asymptomatic patient or the patient with chronic hypomagnesemia should be treated with an oral sustained-release preparation. Mag-Tab SR (magnesium lactate) provides 7 mEq (or 84 mg) of magnesium per tablet. Six to eight tablets should be taken daily in divided doses for severe magnesium depletion. Two to four tablets may be sufficient for mild, asymptomatic patients." (20)
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DOUBLE BENEFITS

Mag-Tab SR's lactate formulation provides more absorbable and bioavailable Mg++ than any other formulation.

Plus, the unique 12-hour continuous release assures unsurpassed absorption and minimal side effects.
Product
Mag-Tab SR
Slow-Mag®
MagOx® 400
Magonate®
Form of magnesium

L-lactate dihydrate

Chloride

Oxide

Gluconate

Elemental Mg++/dose

84 mg

64 mg

241 mg

27 mg

mEq Mg++ per dose

7 mEq

5.26 mEq

19.8 mEq

2.2 mEq

Solubility

Excellent

High

Extremely low

Moderate

Oral Absorption

41.1%

19.68%

2.00%

19.25%

Bioavailable mEq
Mg++ per dose

2.87 mEq

1.04 mEq

0.39 mEq

0.42 mEq

Dose needed to provide
approx. 5.7 mEq bio.
Mg++/day
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Note: Magnesium hydroxide (milk of magnesia), magnesium citrate and magnesium carbonate are not included because of their therapy-limiting side effects (e.g., GI distress, diarrhea) and their very low bioavailability.

Slow-Mag is a registered trademark of Purdue Pharma LP, MagOx is a registered trademark of Hi Tech Pharmacal, and Magonate is a registered trademark of Roberts Pharmaceutical Corp., Blaine Company, Inc., and Fleming & Company respectively.
References: 12. Klein M: CVR&R 1994; (15) 10: 9-56. 20. Kelepouris, E et al: Seminars in Nephrol 1998; 18 (1) 58-73. 30. Gullestad L: Magnes Trace Elem 1991-92; 10 (1): 11-16. 31. White, J Massey L: Clin Ther 1992; 1992 14 (5): 678-687. 32. Linberg JS: J Amer Coll Nutr 1990; 9 (1) 48-55. 33. Knochel TL: Harrison’s Principles of Internal Medicine 1991; 1935-1938. 34. Fine KD: J Clin Invest 1991; 2:396-402. 35. Ranade & Somberg:American Journal of Therapeutics 2001: pg. 8, 345-357.
"The statements on this page have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, cure, or prevent any disease."

Buy Mag-Tab SR

Mag-Tab SR is available by request at your local retail pharmacy in every state in the United States of America. Any pharmacy will, upon insistence, order Mag-Tab SR through their local drug wholesaler. Mag-Tab SR is sold online.

RESOURCES

We have a large number of published magnesium references. Please contact us for specific links or documents

NICHE PHARMACEUTICALS

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Southlake, Texas 76092-9156
800-677-0355
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